Tetracaine Hydrochloride | CAS 94-24-6 | Pharmaceutical Grade Local Anesthetic

Pharmaceutical Overview

Tetracaine Hydrochloride (CAS 94-24-6) is a potent ester-type local anesthetic renowned for its rapid onset and extended duration of action. As the active pharmaceutical ingredient in various numbing eye drops and topical anesthesia products, this compound offers superior mucosal penetration and sustained analgesic effects.

For medical professionals researching what is tetracaine used for, it serves as a cornerstone in ophthalmic procedures, dermatological applications, and veterinary medicine.

The tetracaine hydrochloride salt form provides enhanced stability and water solubility compared to the free base, making it ideal for pharmaceutical formulations requiring precise dosing and reliable performance.

Elite Technical Specifications

• Chemical Name: 2-(Dimethylamino)ethyl 4-(butylamino)benzoate hydrochloride

• Synonyms: Amethocaine Hydrochloride

• CAS Number: 94-24-6

• Molecular Formula: C₁₅H₂₄N₂O₂ · HCl

• Molecular Weight: 300.83 g/mol

• Appearance: White, crystalline powder

• Purity: ≥99% (USP Grade, HPLC-verified)

• Solubility: Freely soluble in water (1:1), soluble in ethanol

• Melting Point: 147-150°C

• pH: 4.5-6.5 (1% aqueous solution)

• Storage: Store in airtight, light-resistant containers at controlled room temperature

Authorized Applications & Uses

Our premium Tetracaine Hydrochloride serves essential roles across multiple medical specialties:

1. Ophthalmic Applications

• Tetracaine eye drops for corneal anesthesia during tonometry and foreign body removal

• Ophthalmic solution for preoperative anesthesia and diagnostic procedures

• Anesthetic eye drops for short-term ocular surface analgesia

• Tetracaine ophthalmic formulations for veterinary eye procedures

2. Topical & Dermatological Use

• Tetracaine cream formulations for skin procedures and surface analgesia

• Lidocaine/tetracaine cream combinations for enhanced dermal anesthesia

• Numbing cream preparations for cosmetic and minor surgical procedures

• Tetracaine ointment for mucosal surface anesthesia

3. Veterinary Medicine

• Neo Predef with tetracaine topical powder for dermatological conditions in animals

• Veterinary ophthalmic solutions for diagnostic and therapeutic procedures

• Topical anesthesia formulations for minor veterinary surgeries

4. Specialized Formulations

• Tetracaine lollipops for oropharyngeal anesthesia

• Numbing lollipops for pediatric procedural sedation

• Dental applications for mucosal surface anesthesia

Clinical & Pharmacological Profile

Understanding Tetracaine’s Medical Applications:

Mechanism of Action:

• Blocks voltage-gated sodium channels in neuronal membranes

• Prevents depolarization and propagation of action potentials

• Provides rapid-onset, reversible local anesthesia

Dosage & Administration:

• Tetracaine eye drops dosage: Typically 1-2 drops of 0.5% solution

• Tetracaine duration of action: 45-60 minutes (longer than many other topical anesthetics)

• Ophthalmic use frequency: Limited to avoid corneal toxicity

Comparative Pharmacology:

• Tetracaine vs proparacaine: Tetracaine offers longer duration but slightly slower onset

• Lidocaine vs tetracaine: Tetracaine provides more potent surface anesthesia

• Tetracaine vs lidocaine: Tetracaine superior for mucosal surface anesthesia

Safety Profile:

• Tetracaine side effects may include transient stinging, corneal clouding with prolonged use

• Contraindications: Hypersensitivity to ester local anesthetics

• Ophthalmic precautions: Avoid extended use due to potential corneal toxicity

⚠️ Critical Safety & Handling Information

WARNING: TETRACAINE HYDROCHLORIDE IS A POTENT LOCAL ANESTHETIC WITH SERIOUS SYSTEMIC TOXICITY POTENTIAL IF ABSORBED. It must be used only under appropriate medical supervision.

Safety Data:

• Tetracaine hydrochloride can cause methemoglobinemia in excessive doses

• Ophthalmic use requires careful dosing to prevent corneal damage

• Systemic absorption may cause CNS and cardiovascular effects

• Not for unsupervised consumer use

Handling Protocols:

• Use appropriate PPE: nitrile gloves, lab coat, and safety goggles

• Handle in controlled laboratory or pharmaceutical environments

• Follow aseptic techniques for pharmaceutical compounding

• Store in secure, temperature-controlled conditions

Order Now – For Qualified Professionals Only

Secure Your Pharmaceutical-Grade Anesthetic
Ensure the highest quality in your medical formulations with our certified Tetracaine Hydrochloride.

USP PHARMACEUTICAL GRADE:

• Batch-specific Certificate of Analysis

• HPLC purity verification ≥99%

• Full USP compliance documentation

• cGMP manufacturing standards

Available Quantities:

• 10 Grams(Ideal for compounding pharmacies)

• 50 Grams(Ophthalmic formulation development)

• 100 Grams(Small-scale manufacturing)

• 500 Grams  (Production quantities)

• 1 Kilogram (Large-scale manufacturing)

Every order includes:

• Certificate of Analysis (CoA) with full USP testing data

• Material Safety Data Sheet (MSDS)

• USP Compliance Documentation

• Regulatory Support Documents

• Secure, Pharmaceutical-Grade Packaging

⚖️ Legal Disclaimer

This product, Tetracaine Hydrochloride (CAS 94-24-6), is sold strictly as a pharmaceutical ingredient for compounding, manufacturing, and research applications by qualified professionals. It is NOT for consumer use. The buyer is 100% responsible for ensuring compliance with all local, state, and federal regulations regarding the purchase, handling, and use of this material. Proof of professional credentials and intended legitimate use may be required.