Procaine Hydrochloride | CAS 51-05-8 | USP Grade Local Anesthetic Powder

Comprehensive Pharmaceutical Overview

Procaine Hydrochloride (CAS 51-05-8), historically and commonly known as Novocaine, represents one of the first synthetic local anesthetics and remains a fundamental compound in medical and dental practice. For those researching what is procaine, it is an ester-type local anesthetic that revolutionized pain management in clinical settings.

This procaine HCl powder is provided in United States Pharmacopeia (USP) grade quality, ensuring the highest standards of purity and consistency for pharmaceutical applications. As a procaine local anesthetic, it works by blocking sodium channels in neuronal membranes, preventing the initiation and conduction of nerve impulses.

Elite Technical Specifications

• Chemical Name: 2-Diethylaminoethyl 4-aminobenzoate hydrochloride

• Synonyms: Novocaine, Procaine HCl

• CAS Number: 51-05-8

• Molecular Formula: C₁₃H₂₀N₂O₂ · HCl

• Molecular Weight: 272.77 g/mol

• Appearance: White, crystalline powder

• Purity: ≥99% (USP Grade, HPLC-verified)

• Solubility: Freely soluble in water (1:1), soluble in ethanol

• Melting Point: 156-158°C

• pH: 5.0-6.5 (1% aqueous solution)

• Storage: Store in airtight, light-resistant containers at controlled room temperature

Authorized Applications & Uses

Our premium Procaine Hydrochloride serves essential roles across medical and research fields:

1. Pharmaceutical Compounding & Manufacturing

• Dental Anesthesia: Primary ingredient in local anesthetic formulations for dental procedures

• Injectable Formulations: Used in procaine injections and procaine 2 injection products for minor surgical procedures

• Topical Preparations: Component of anesthetic creams and ointments for surface analgesia

2. Clinical Applications

• Infiltration Anesthesia: For minor surgical procedures and wound repair

• Nerve Block Anesthesia: For regional pain control in specific anatomical areas

• Therapeutic Injections: Used in some pain management protocols

3. Research & Development

• Comparative Studies: Research into mechanisms of local anesthesia and comparisons with newer agents

• Pharmacological Research: Studies of ester-based anesthetics and their metabolism

• Formulation Development: Development of novel delivery systems for local anesthetics

Clinical & Pharmacological Profile

Understanding Procaine’s Medical Applications:

Mechanism of Action:

• Blocks voltage-gated sodium channels in neuronal membranes

• Prevents depolarization and propagation of action potentials

• Provides reversible loss of sensation in specific areas

Therapeutic Uses:

• Procaine uses include dental procedures, minor surgery, and diagnostic procedures

• Procaine hydrochloride uses encompass various infiltration and nerve block techniques

• Procaine HCl uses are well-established in clinical practice with decades of safety data

Pharmacokinetics:

• Rapid onset of action (5-10 minutes)

• Moderate duration of effect (30-60 minutes)

• Metabolized by plasma esterases to para-aminobenzoic acid (PABA) and diethylaminoethanol

Safety Considerations:

• Generally well-tolerated with proper administration

• Potential for allergic reactions in sensitive individuals

• CNS and cardiovascular effects at excessive doses

• Contraindicated in patients with ester local anesthetic hypersensitivity

⚠️ Critical Safety & Handling Information

WARNING: PROCAINE HYDROCHLORIDE IS A POTENT PHARMACEUTICAL AGENT WITH SPECIFIC CLINICAL INDICATIONS. It is NOT for consumer use. This product is sold strictly to qualified professionals for pharmaceutical compounding, research, and manufacturing applications.

Safety Data:

• Procaine drug classification: Local anesthetic (ester type)

• Potential for systemic effects if improperly administered

• Requires proper medical supervision for clinical use

• Follow all appropriate safety protocols when handling

Handling Protocols:

• Use in controlled laboratory or pharmaceutical environments only

• Wear appropriate PPE: nitrile gloves, lab coat, and safety goggles

• Handle under appropriate ventilation when working with powders

• Store in secure, temperature-controlled conditions

• Follow aseptic techniques for pharmaceutical compounding

📦 Order Now – For Qualified Professionals Only

Secure Your Pharmaceutical-Grade Anesthetic
Ensure the highest quality in your formulations with our certified Procaine Hydrochloride.

USP PHARMACEUTICAL GRADE:

• Batch-specific Certificate of Analysis

• HPLC purity verification ≥99%

• Full USP compliance documentation

• cGMP manufacturing standards

Available Quantities:

• 10 Grams – $30 (Ideal for research and development)

• 50 Grams – $150 (Compounding pharmacy applications)

• 100 Grams – $1500 (Small-scale manufacturing)

• 500 Grams – $5000 (Production quantities)

• 1 Kilogram – $10000 (Large-scale manufacturing)

Every Order Includes:

• Certificate of Analysis (CoA) with full USP testing data

• Material Safety Data Sheet (MSDS)

• USP Compliance Documentation

• Regulatory Support Documents

• Secure, Pharmaceutical-Grade Packaging

⚖️ Legal Disclaimer

This product, Procaine Hydrochloride (CAS 51-05-8), is sold strictly as a pharmaceutical ingredient for compounding, manufacturing, and research applications by qualified professionals. It is NOT for consumer use. The buyer is 100% responsible for ensuring compliance with all local, state, and federal regulations regarding the purchase, handling, and use of this material. Proof of professional credentials and intended legitimate use may be required.