Lidocaine Hydrochloride | CAS 73-78-9 | USP Grade Local Anesthetic API

Comprehensive Pharmaceutical Overview

Lidocaine Hydrochloride (CAS 73-78-9) represents the global gold standard in local anesthesia, serving as the active pharmaceutical ingredient in countless medical formulations worldwide. For those researching what is lidocaine, it is an amide-type local anesthetic that revolutionized pain management through its rapid onset, intermediate duration, and excellent safety profile.

This lidocaine hydrochloride powder is manufactured to United States Pharmacopeia (USP) standards, ensuring uncompromised purity and consistency for pharmaceutical compounding and manufacturing.

As the most versatile local anesthetic agent, lidocaine serves as the foundation for formulations ranging from lidocaine injection solutions to lidocaine cream and viscous lidocaine preparations for mucosal application.

Elite Technical Specifications

• Chemical Name: 2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide hydrochloride

• Synonyms: Lignocaine Hydrochloride

• CAS Number: 73-78-9

• Molecular Formula: C₁₄H₂₂N₂O · HCl

• Molecular Weight: 270.80 g/mol

• Appearance: White, crystalline, hygroscopic powder

• Purity: ≥99% (USP Grade, HPLC-verified)

• Solubility: Freely soluble in water (1:1), soluble in ethanol (1:2)

• Melting Point: 75-78°C

• pH: 4.0-5.5 (1% aqueous solution)

• Storage: Store in airtight, light-resistant containers with desiccant at 15-30°C

Authorized Applications & Uses

Our premium Lidocaine Hydrochloride powder enables formulation of diverse medical products:

1. Topical Anesthetic Formulations

• Lidocaine cream preparations (1%, 2%, 4%, 5% concentrations)

• Lidocaine gel for mucosal and surface anesthesia

• Lidocaine ointment USP 5% for dermatological use

• Topical lidocaine solutions for pre-procedural skin preparation

2. Injectable Anesthetics

• Lidocaine injection solutions for infiltration and nerve block

• Lidocaine HCl injection USP in various concentrations (0.5%, 1%, 2%)

• Lidocaine ampoules for single-use medical procedures

• Regional anesthesia formulations for surgical use

3. Mucosal & Oral Preparations

• Viscous lidocaine solutions for oropharyngeal anesthesia

• Lidocaine oral solution for painful mouth conditions

• Lidocaine mouth rinse for dental procedures

• Lidocaine jelly for urological and endoscopic procedures

4. Specialized Medical Compounding

• Custom concentration lidocaine topical formulations

• Lidocaine hydrochloride cream for specific patient needs

• Veterinary anesthetic preparations

• Combination products with other therapeutic agents

Clinical & Pharmacological Profile

Understanding Lidocaine’s Medical Applications:

Mechanism of Action:

• Potent voltage-gated sodium channel blockade

• Prevents neuronal depolarization and action potential propagation

• Rapid onset (2-5 minutes) with duration of 1-2 hours

Dosage & Administration:

• Topical use: 1-5% concentrations for surface anesthesia

• Injectable use: 0.5-2% solutions for infiltration anesthesia

• Mucosal use: 2% viscous lidocaine for oropharyngeal pain

• Maximum dose: 4.5 mg/kg (without epinephrine)

Therapeutic Uses:

• What is lidocaine used for: Local anesthesia, cardiac arrhythmias, neuropathic pain

• Lidocaine uses: Surgical anesthesia, dental procedures, dermatological treatments

• Lidocaine hydrochloride used for: Multiple medical applications across specialties

Safety Considerations:

• Generally excellent safety profile when properly administered

• Potential for systemic toxicity at excessive doses

• Requires appropriate medical supervision for injectable use

⚠️ Critical Safety & Handling Information

WARNING: LIDOCAINE HYDROCHLORIDE IS A POTENT PHARMACEUTICAL AGENT WITH CARDIAC AND NEUROLOGICAL EFFECTS AT HIGH DOSES. Proper handling and professional use are mandatory.

Safety Protocols:

• Use appropriate PPE: nitrile gloves, lab coat, and safety goggles

• Handle in controlled pharmaceutical environments only

• Implement engineering controls for powder handling

• Follow strict aseptic techniques for formulation work

Professional Use Only:

• Not for over-the-counter consumer use without proper formulation

• Requires medical supervision for injectable administration

• Lidocaine hydrochloride powder must be properly formulated before use

• Follow all applicable regulatory guidelines

Order Now – For Qualified Professionals Only

Secure Your Pharmaceutical-Grade Anesthetic
Ensure the highest standard of patient care with our certified Lidocaine Hydrochloride.

USP PHARMACEUTICAL GRADE:

• Batch-specific Certificate of Analysis

• HPLC purity verification ≥99%

• Full USP compliance documentation

• cGMP manufacturing standards

• Comprehensive stability data

Available Quantities:

• 50 Grams – $20 (Ideal for compounding pharmacies)

• 250 Grams – $100 (Small-scale manufacturing)

• 1 Kilogram – $400 (Production quantities)

• 5 Kilograms – $2000 (Large-scale manufacturing)

• 25 Kilograms – $10000 (Industrial-scale production)

Every Order Includes:

• Certificate of Analysis (CoA) with full USP testing data

• Material Safety Data Sheet (MSDS)

• USP Compliance Documentation

• Regulatory Support Documents

• Secure, Pharmaceutical-Grade Packaging

⚖️ Legal Disclaimer

This product, Lidocaine Hydrochloride (CAS 73-78-9), is sold strictly as a pharmaceutical ingredient for compounding, manufacturing, and research applications by qualified professionals. It is NOT for consumer use. The buyer is 100% responsible for ensuring compliance with all local, state, and federal regulations regarding the purchase, handling, and use of this material. Proof of professional credentials and intended legitimate use may be required.